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Abstract
Coordination compound of Mn(II) with newly synthesized Schiff base ligand (E)-3-(1-(2-(benzo[d]thiazol-2yl)hydrazono)ethyl)-1-ethyl-4-hydroxyquinolin-2(1H)-one. The obtained ligand and Mn(II) complex is characterized on the basis of elemental analysis, magnetic susceptibility, UV visible spectra, FTIR ,1HNMR spectra, mass spectra, TG-DTA and X-ray powder diffraction. Form the analytical data the stoichiometry of metal complex has been found to be the 2:1 ligand to metal ratio. Therefore the complex may be formulated as [Mn(L2)]. All the analysis data shows that complex is monomeric hexa coordinated octahedral structure. The ligand and metal chealate have been screened for their antibacterial activity using the Agar cup method at fixed concentration of 1% Against microbial strains, Eschershia coli, Salmonalla typhi, Staphylococcus aureus, Bacillus substilis. The antibacterial activity of ligand and Mn(II) complex illustrates that the ligand and complex seems to be inert towards the E. coli , S. typhi the complex show higher activity than ligand against Staphylococcus aureus and Bacillus substill. Antifungal activity of ligand and complex were tested against in vitro against fungi that is Aspergillus niger, Penicilum chrysoganum, Fusarium moniliforme, Aspergillus flavus by poison plate method using potato dextrose agar medium at fixed (1%) concentration. Ligand does not show fungal activity but it Mn(II) complex show better activity. Which suggest that the incorporation of metal in the ligand results in increasing the antimicrobial activity. X-ray diffraction data suggests triclinic structure of Mn(II) complex.