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Locke believes that we acquire all knowledge through sense-experience. Locke under the profound influence of the rationalist thinker Descartes, accepts that what we directly receive through sense-experience are only simple ideas' Nevertheless, he attempts to account for our knowledge of the material world by introducing the 'complex ideas' of substance, modes and relations, which are formed out of the 'simple ideas' through the rational operations of the mind. One of Locke's epistemological objectives is to validate scientific knowledge in its two essential prerequisites, namely material substance and causal connections. Locke said that sometimes we do not observe the relation or difference between two ideas and indirectly establish a relation between the two.

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