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Abstract
The health risk behavior of TG and MSM are very alarming in recent time. They are always at high risk due to their behavioral pattern which is culturally shaped and produced. MSM and TG community is always at high risk because of their behavior is culturally. The present paper seeks to understand their behavioral pattern which induced them in danger. Some of the questions i.e. what their affect their mental and physical health and how culture have led a significant role in affecting their health. These questions are empirically interpreted and examine from the field site of Varanasi. To do show, this paper employs a qualitative research design guided by case study method. The paper concludes the health risk behavior of MSM is higher than TG due to high emotions, stigmised behavior and negativity and towards life.